Neptune, the Pisces ruler, rules the immune system. (Think of all the air born diseases – SARS and such – while Neptune was in Aquarius over the past 14 years.) If the Moon in Pisces makes contact to your natal Neptune (or Saturn)and if the 6th house is somehow involved, I believe it could trigger a disease. I know of two people who became sick when moon entered Pisces – they blame it on the apartment being painted (so Neptunian), but I believe it has also a strong psychological source.
Moon affects women more than in male charts. It depends on the aspects it receives because Moon is neutral just like Mercury and needs aspects for expression. The sickness associated with Moon / Pisces has to do with nutrition, and nervous disorers.
As Pisces rules the feet, when the Moon is in this sign, reflexology can be an especially lovely activity to engage in. The massaging of pressure points on the feet can help to circulate energy.
I’ve seen so much of this among my Pisces friends:
“My feeling is that Pisces Moon people can, especially earlier in life, have a much harder time than other people with addiction – to drugs and alcohol, sure, but also and perhaps more frequently to energy vampires and to the kind of sexuality and/or fantasy that promises union with the Divine but ultimately leaves the native drained, depleted and disillusioned.
Where Pisces Sun natives are especially prone to physical addiction (Sun = the body), Pisces Moon natives are more drawn to psychological or emotional addictions."
by D.K. Brainard
Real life is not really to your taste; it can be too harsh and demanding, making too great an impact on your malleable feelings and wearing you down through constant emotional agitation. You may seek escape through imagination, fantasies, dreams,and addictions, such as alcohol, drugs, and sexual activity. Prolonged exposure to your private dream world may make you less able to deal wityh the demands of human existence; and time and effort may be spent in dreaming of a better futurerather than actually working to make it a reality. (Haydn Paul)